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Many members of the species suffer debilitating diseases which make them either run around acting all crazy or holding up and confining themselves in their burrows. Some colonies even enforce these confinments so that the disease does not spread to their essential service providers who deliver food and work making the colony's utilities function, like carrying all the shit, piss and rubbish the heavy consumption lifestyle promoted by the leaders of the colony have convinced those lower down in the hierarchy to follow. So you can imagine the frenzy and panic which grips the colony when a pandemic occurs, which is inevitable when any species is overcrowded in unnatural permanent dwellings in symbiotic relationships with viruses and bacteria.